{"id":205467,"date":"2018-04-17T08:43:01","date_gmt":"2018-04-17T08:43:01","guid":{"rendered":"http:\/\/research.iitgn.ac.in\/ccbl\/publications\/"},"modified":"2025-11-11T06:38:28","modified_gmt":"2025-11-11T06:38:28","slug":"publications","status":"publish","type":"page","link":"http:\/\/labs.iitgn.ac.in\/crystallab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; background_color=&#8221;#E02B20&#8243; use_background_color_gradient=&#8221;on&#8221; background_color_gradient_stops=&#8221;#7cda24 0%|#2b87da 100%&#8221; background_color_gradient_start=&#8221;#7cda24&#8243; background_color_gradient_end=&#8221;#2b87da&#8221; background_image=&#8221;http:\/\/labs.iitgn.ac.in\/crystallab\/wp-content\/uploads\/2018\/04\/Crystal-4.jpg&#8221; parallax=&#8221;on&#8221; custom_padding=&#8221;0px|0px|0px|0px&#8221; background_color_gradient_stops_tablet=&#8221;#7cda24 0%|#2b87da 100%&#8221; background_color_gradient_stops_phone=&#8221;#7cda24 0%|#2b87da 100%&#8221; global_module=&#8221;205494&#8243; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_fullwidth_header _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#1c1c1c&#8221; inline_fonts=&#8221;Amethysta&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 class=\"et_pb_module_header et-fb-editable-element et-fb-editable-element__editing\" data-shortcode-id=\"0.0-1737381063290\" data-quickaccess-id=\"title\" contenteditable=\"true\" style=\"text-align: center;\"><span style=\"font-family: Amethysta;\"><strong>MACROMOLECULAR AND CHEMICAL CRYSTALLOGRAPHY LAB (MCCL)<\/strong><\/span><\/h1>\n<p>[\/et_pb_fullwidth_header][et_pb_fullwidth_menu menu_id=&#8221;7&#8243; submenu_direction=&#8221;downwards&#8221; fullwidth_menu=&#8221;on&#8221; _builder_version=&#8221;4.21.0&#8243; menu_font=&#8221;|800|||||||&#8221; menu_text_color=&#8221;#0011d6&#8243; background_color=&#8221;#e5e5e5&#8243; text_orientation=&#8221;center&#8221; menu_text_shadow_style=&#8221;preset3&#8243; global_colors_info=&#8221;{}&#8221;][\/et_pb_fullwidth_menu][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|0px|0px|0px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_text _builder_version=&#8221;4.16&#8243; global_colors_info=&#8221;{}&#8221;]<\/p>\n<h1 style=\"text-align: center;\"><strong>Publications<\/strong><\/h1>\n<p>[\/et_pb_text][et_pb_toggle title=&#8221;2025&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; width=&#8221;94%&#8221; module_alignment=&#8221;center&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li><span>Chadha, Prashsti, Hiral Aghara, Harshrajsinh Solanki, Manali Patel, Dhrubjyoti Sharma, Vijay Thiruvenkatam, and PALASH MANDAL. &#8220;Modulation of TNF\u03b1-driven neuroinflammation by Gardenin A: Insights from In Vitro, In Vivo, and In Silico studies.&#8221;\u00a0<\/span><i>Frontiers in Pharmacology<\/i><span> 16: 1681403. DOI: <a href=\"https:\/\/doi.org\/10.3389\/fphar.2025.1681403\">https:\/\/doi.org\/10.3389\/fphar.2025.1681403<\/a>\u00a0<\/span><\/li>\n<li>Anandan A, Venkatesan P, Thiruvenkatam V, Percino MJ, Thamotharan S. Crystallographic and computational insights into charge-assisted N\/C\u2013H\u00b7\u00b7\u00b7 Br\u2212 hydrogen bonding in 2-Amino-1-alkylpyridinium bromide salts. Journal of Molecular Liquids. 2025 Oct 21:128764. DOI:\u00a0 <a href=\"https:\/\/doi.org\/10.1016\/j.molliq.2025.128764\">https:\/\/doi.org\/10.1016\/j.molliq.2025.128764<\/a>\u00a0<\/li>\n<li>Dilip, Haritha, Vijay Thiruvenkatam, and Sivapriya Kirubakaran. &#8220;IMPDH as a potential antibacterial drug target for microbial infections: A review on a decade of targeted therapy and its implications.&#8221; <em>Drug Discovery Today, <\/em>2025: 104505. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.drudis.2025.104505\">https:\/\/doi.org\/10.1016\/j.drudis.2025.104505<\/a>\u00a0<\/li>\n<li>Dilip, Haritha, Deepika Khasa, Ramya VK, Parvinder Kaur, Siva Shanmugam, Naveenkumar Chakenalli, Radhakrishanan Shandil, Shridhar Narayanan, Vijay Thiruvenkatam, and Sivapriya Kirubakaran. &#8220;Studies on developing a preclinical candidate to fight Helicobacter Pylori infection.&#8221; <em>ACS Infectious Diseases<\/em> 11, no. 8, 2025: 2367-2371.<\/li>\n<li>Jebaraj, Paul Daniel, Michael Purushothaman, Karuppiah Loganathan, M. Judith Percino, Vijay Thiruvenkatam, and Perumal Venkatesan. &#8220;Impact of chlorine substitution on supramolecular architecture and non-covalent interactions in Ethyl 2-amino-6-chloro-4-aryl-7-hydroxy-4 H-benzo [4, 5-e] pyran-3-carboxylate Isomers: a combined experimental, crystallographic, theoretical, and antioxidant study.&#8221; Structural Chemistry, 2025: 1-21. DOI: <span><a href=\"https:\/\/doi.org\/10.1007\/s11224-025-02557-9\">https:\/\/doi.org\/10.1007\/s11224-025-02557-9<\/a> <\/span>\u00a0<\/li>\n<li><span>Choudhary, Mahendra B., Delna Johnson, Deep Kumar Das, Vijay Thiruvenkatam, Janardan Kundu, and Venkatesha R. Hathwar. &#8220;Effect of synthesis methods, biocompatibility and photoluminescence of scheelite type sodium lanthanide double tungstates.&#8221;\u00a0<\/span><i>Scientific Reports<\/i><span> 15, no. 1, 2025: 20605. DOI:\u00a0<\/span><span class=\"c-bibliographic-information__value\"><a href=\"https:\/\/doi.org\/10.1038\/s41598-025-93239-3\">https:\/\/doi.org\/10.1038\/s41598-025-93239-3<\/a>\u00a0<\/span><\/li>\n<li>Chadha, Prashsti, Hiral Aghara, Delna Johnson, Dhrubjyoti Sharma, Mitalben Odedara, Manali Patel, Hemant Kumar, Vijay Thiruvenkatam, and Palash Mandal. &#8220;Gardenin A alleviates alcohol-induced oxidative stress and inflammation in HepG2 and Caco2 cells via AMPK\/Nrf2 pathway.&#8221; <em>Bioorganic Chemistry,<\/em>161, 2025: 108543. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108543\">https:\/\/doi.org\/10.1016\/j.bioorg.2025.108543<\/a>\u00a0<span class=\"c-bibliographic-information__value\"><\/span><\/li>\n<li><span>Johnson, Delna, Shivangi Sharma, Vijay Thiruvenkatam, and Sivapriya Kirubakaran. &#8220;Characterization of new non-ATP dependent inhibitors of TLK1 as potential molecules for treating prostate cancer.&#8221;\u00a0<\/span><i>Bioorganic Chemistry<\/i><span> 158, 2025: 108317. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108317\">https:\/\/doi.org\/10.1016\/j.bioorg.2025.108317<\/a>\u00a0<\/span><span class=\"c-bibliographic-information__value\"><\/span><\/li>\n<li><span>Venkatesan, Perumal, Vijay Thiruvenkatam, M. Judith Percino, and Subbiah Thamotharan. &#8220;Evaluation of Charge-Assisted Hydrogen Bonds and Weak Intermolecular Interaction in Trimethoprim 2-Aminobenzoate: A Combined Crystallographic and Theoretical Approach.&#8221;\u00a0<\/span><i>Judith and Thamotharan, Subbiah, Evaluation of Charge-Assisted Hydrogen Bonds and Weak Intermolecular Interaction in Trimethoprim<\/i><span>. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.molstruc.2024.139644\">https:\/\/doi.org\/10.1016\/j.molstruc.2024.139644<\/a>\u00a0<\/span><span><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_toggle][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;0px|0px|50.5938px|0px&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_row admin_label=&#8221;Year (2019)&#8221; _builder_version=&#8221;4.21.0&#8243; background_color=&#8221;#FFFFFF&#8221; max_width=&#8221;1018px&#8221; min_height=&#8221;1000px&#8221; custom_padding=&#8221;27px|0px|0px|0px&#8221; global_module=&#8221;206004&#8243; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;4.16&#8243; custom_padding=&#8221;|||&#8221; global_colors_info=&#8221;{}&#8221; custom_padding__hover=&#8221;|||&#8221;][et_pb_accordion _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_accordion_item title=&#8221;2024&#8243; open=&#8221;on&#8221; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<ul>\n<li>Priya, Bhanu, Delna Johnson, Gurudutt Dubey, Divita Suthar, Indracanti Prem Kumar, Vijay Thiruvenkatam, and Sivapriya Kirubakaran. &#8220;Temozolomide cocrystal forms with enhanced dissolution, stability and biological activity towards Glioblastoma.&#8221; <em>Journal of Molecular Structure<\/em> : 138751, 2024. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.molstruc.2024.138751\">https:\/\/doi.org\/10.1016\/j.molstruc.2024.138751<\/a>\u00a0<\/li>\n<li>Dilip, Haritha, Vijay Thiruvenkatam, and Sivapriya Kirubakaran. &#8220;Studies on Methylpyrazole-Substituted Benzimidazoles to Target Helicobacter pylori Infection through Hp IMPDH Inhibition.&#8221; <em>ACS Infectious Diseases<\/em>, 2024. DOI:<a href=\"https:\/\/doi.org\/10.1021\/acsinfecdis.4c00228\">https:\/\/doi.org\/10.1021\/acsinfecdis.4c00228<\/a>\u00a0<\/li>\n<li>Shah, Sakshi M., Soumalya Chakraborty, Gurudutt Dubey, Suhas Yewale, Rohit Y. Sathe, L. Ramaswamy, Samir Haddouchi, Vijay Thiruvenkatam, Prasad V. Bharatam, and Arvind K. Bansal. &#8220;Effect of Differential Surface Anisotropy on Dissolution Behavior of Fenofibrate Crystal Habits: Comparative Study using USP Type 2 and Type 4 Dissolution Apparatuses.&#8221; <em>Journal of Pharmaceutical Sciences<\/em>, 2024. DOI: <a href=\"https:\/\/doi.org\/10.1016\/j.xphs.2024.02.001\">https:\/\/doi.org\/10.1016\/j.xphs.2024.02.001<\/a>\u00a0<\/li>\n<li>Choubey, Rinku, Moumita Chatterjee, Delna Johnson, Vijay Thiruvenkatam, Akshant Kumawat, Abhijit Mishra, and Bhaskar Datta. &#8220;Tunable Coassembly of Octaarginine with Thiazolyl Benzenesulfonamides Exerts Variable Antibacterial Activity.&#8221; <em>The Journal of Physical Chemistry<\/em> B 128, no. 42, 2024: 10434-10450. DOI: <a href=\"https:\/\/doi.org\/10.1021\/acs.jpcb.4c03336\">https:\/\/doi.org\/10.1021\/acs.jpcb.4c03336<\/a>\u00a0<\/li>\n<li>Parwani, Kirti, Farhin Patel, Pranav Bhagwat, Haritha Dilip, Dhara Patel, Vijay Thiruvenkatam, and Palash Mandal. &#8220;Swertiamarin mitigates nephropathy in high-fat diet\/streptozotocin-induced diabetic rats by inhibiting the formation of advanced glycation end products.&#8221; Archives of physiology and biochemistry 130, no. 2, 2024: 136-154. DOI: <a href=\"https:\/\/doi.org\/10.1080\/13813455.2021.1987478\">https:\/\/doi.org\/10.1080\/13813455.2021.1987478<\/a>\u00a0<\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2023&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<ul>\n<li style=\"text-align: justify;\">Sivadas, Deepanjaly K.; Ravi, Sasikala; Nagarasu, Palaniyappan; George, Johnson Delna J. K.; Thiruvenkatam, Vijay; Anthony, Savarimuthu Philip and Madhu, Vedichi, \u201cFluorophore unit controlled photoswitching of hydrazone derivatives: reversible and irreversible off-on\/dual-color fluorescence photoswitches\u201d,\u00a0<em>Molecular Systems Design &amp; Engineering<\/em>, Jul. 2023. DOI: <a href=\"https:\/\/pubs.rsc.org\/en\/content\/articlehtml\/2023\/me\/d3me00093a\">https:\/\/doi.org\/10.1039\/D3ME00093A<\/a><\/li>\n<li style=\"text-align: justify;\">Singh, Surendra V.; Jayaram, V.; Meka, Jaya K.;\u00a0Thiruvenkatam, Vijay; Vijayan, S.; Bhardwaj, Anil; Burchell, M. J.; Mason, N. J. and Sivaraman, B., \u201cExtraterrestrial impacts creating architectures for life\u201d,\u00a0<em>Journal of the Indian Institute of Science<\/em>, Jul. 2023. DOI:\u00a0<a href=\"https:\/\/link.springer.com\/article\/10.1007\/s41745-023-00397-2\" target=\"_blank\" rel=\"noopener\">10.1007\/s41745-023-00397-2<\/a><\/li>\n<li style=\"text-align: justify;\">Shaik, Althaf; Bhagwat, Pranav; Palanisamy, Parimaladevi; Chhabria, Dimple; Dubey, Pankaj; Kirubakaran, Sivapriya\u00a0and\u00a0Thiruvenkatam, Vijay, \u201cNovel pharmaceutical co-crystals of gefitinib: synthesis, dissolution, cytotoxicity, and theoretical studies\u201d,\u00a0<em>CrystEngComm<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1039\/D3CE00056G\" target=\"_blank\" rel=\"noopener\">10.1039\/D3CE00056G<\/a>, vol. 25, no. 17, pp. 2570-2581, Mar. 2023.<\/li>\n<li style=\"text-align: justify;\">George, Johnson Delna J. K.; Hussain, Javeena; Bhoir, Siddhant; Chandrasekaran, Vaishali; Sahrawat, Parul; Hans, Tanya; Khalil, Md Imtiaz; Benedetti, Arrigo De;\u00a0Thiruvenkatam, Vijay\u00a0and\u00a0Kirubakaran, Sivapriya, \u201cSynthesis, kinetics and cellular studies of new phenothiazine analogs as potent human-TLK inhibitors\u201d,\u00a0<em>Organic &amp; Biomolecular Chemistry<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1039\/D2OB02191A\" target=\"_blank\" rel=\"noopener\">10.1039\/D2OB02191A<\/a>, vol. 21, no. 9, pp. 1980-1991, Jan. 2023.<\/li>\n<li style=\"text-align: justify;\">Dahiwadkar, Rahul; Murugan, Arumugavel; George, Johnson Delna J. K.; Chakraborty, Rik; Thiruvenkatam, Vijay\u00a0and\u00a0Kanvah, Sriram, \u201cFunctional organogel with \u03b1-cyanostilbene scaffold: aggregation enhanced emission and picric acid sensing\u201d,\u00a0<em>Journal of Photochemistry and Photobiology A: Chemistry<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.jphotochem.2022.114227\" target=\"_blank\" rel=\"noopener\">10.1016\/j.jphotochem.2022.114227<\/a>, vol. 434, Jan. 2023.<\/li>\n<li style=\"text-align: justify;\">Dahiwadkar, Rahul; Dubey, Gurudutt; Shaik, Althaf; Jana, Palash; Thiruvenkatam, Vijay\u00a0and\u00a0Kanvah, Sriram, \u201cHalogen-bonded co-crystals with AIE active alpha-cyanostilbenes\u201d,\u00a0<em>New Journal of Chemistry<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1039\/D3NJ00333G\" target=\"_blank\" rel=\"noopener\">10.1039\/D3NJ00333G<\/a>, vol. 47, no. 24, pp. 11685-11696, May 2023.<\/li>\n<li style=\"text-align: justify;\">Angira, Deekshi; Chaudhary, Sonali; Abiramasundari, Arumugam\u00a0and\u00a0Thiruvenkatam, Vijay, \u201cTo explore the binding affinity of human \u03b3-secretase activating protein (GSAP) isoform 4 with APP-C99 peptides\u201d,\u00a0<em>ACS Omega<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1021\/acsomega.3c01117\" target=\"_blank\" rel=\"noopener\">10.1021\/acsomega.3c01117<\/a>, vol. 8, no. 14, pp. 13435-13443, Apr. 2023.<\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2022&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<ul>\n<li style=\"text-align: justify;\">George, Johnson Delna J. K.; Hussain, Javeena; Bhoir, Siddhant; Sahsrawat, Parul; Hans, Tanya; Vaishali, C.; Thiruvenkatam, Vijay\u00a0and\u00a0Kirubakaran, Sivapriya, \u201cEvaluating the therapeutic viability of bacterially expressed human TLK1B-kinase domain for cancer drug design\u201d,\u00a0<em>Research Square<\/em>, Research Square Company, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.21203\/rs.3.rs-1314176\/v1\" target=\"_blank\" rel=\"noopener\">10.21203\/rs.3.rs-1314176\/v1<\/a>, Feb. 2022.<\/li>\n<li style=\"text-align: justify;\">Singh, Surendra Vikram; Jayaram, V.; Meka, J. K.; Muruganantham, M.;\u00a0Thiruvenkatam, Vijay; Vijayan, S.; Rajsekhar, B. N.; Bhardwaj, A.; Mason, N. J. and Sivaraman, B., \u201cThree-dimensional complex architectures observed in shock processed amino acid mixtures\u201d,\u00a0<em>Experimental Results<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1017\/exp.2021.17\" target=\"_blank\" rel=\"noopener\">10.1017\/exp.2021.17<\/a>, vol. 3, Feb. 2022.<\/li>\n<li style=\"text-align: justify;\">Singh, Surendra Vikram; Dilip, Haritha; Meka, Jaya K.;\u00a0Thiruvenkatam, Vijay; Jayaram, Vishakantaiah; Muruganantham, Mariyappan; Sivaprahasam, Vijayan; Rajasekhar, Balabhadrapatruni N.; Bhardwaj, Anil; Mason, Nigel J.; Burchell, Mark J. and Sivaraman, Bhalamurugan, \u201cNew signatures of bio-molecular complexity in the hypervelocity impact ejecta of icy moon analogues\u201d,\u00a0<em>Life<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.3390\/life12040508\" target=\"_blank\" rel=\"noopener\">10.3390\/life12040508<\/a>, vol. 12, no. 4, Mar. 2022.<\/li>\n<li style=\"text-align: justify;\">Roy, Arijit; Singh, Surendra Vikram; Meka, J. K.; Ramachandran, R.; Sahu, D.;\u00a0Gautam, Abhay Raj Singh; Thiruvenkatam, Vijay; Jayaram, V.; Janardhan, P.; Rajasekhar, B. N.; Bhardwaj, Anil; Mason, N. J. and Sivaraman, B., \u201cShock induced transformation of non-magnetic to magnetic ISM dust analogue\u201d,\u00a0<em>Monthly Notices of the Royal Astronomical Society<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1093\/mnras\/stac2637\" target=\"_blank\" rel=\"noopener\">10.1093\/mnras\/stac2637<\/a>, vol. 517, no. 4, pp. 4845-4855, Dec. 2022.<\/li>\n<li style=\"text-align: justify;\">Ovais Dar, Mohammad; Kapse, Rahul Y.;\u00a0Dubey, Gurudutt; Singh, Tejender;\u00a0Thiruvenkatam, Vijay\u00a0and Bharatam, Prasad V., \u201cElectronic structure analysis and synthesis of Nitroso N-Heterocyclic Imines\u201d,\u00a0<em>ChemistrySelect<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1002\/slct.202203613\" target=\"_blank\" rel=\"noopener\">10.1002\/slct.202203613<\/a>, vol. 7, no. 43, Nov. 2022.<\/li>\n<li style=\"text-align: justify;\">Hussain, Javeena; Sahrawat, Parul; Dubey, Pankaj; Kirubakaran, Sivapriya\u00a0and\u00a0Thiruvenkatam, Vijay, \u201cExploring packing features of N-substituted acridone derivatives: synthesis and X-ray crystallography studies\u201d,\u00a0<em>Journal of Molecular Structure<\/em>, DOI:\u00a0<a href=\"http:\/\/dx.doi.org\/10.1016\/j.molstruc.2021.131448\" target=\"_blank\" rel=\"noopener\">10.1016\/j.molstruc.2021.131448<\/a>, vol. 1248, Jan. 2022.<\/li>\n<li style=\"text-align: justify;\">Dilip, Haritha; Purushothaman, Gayathri; Sharma, Gaurav; Menon, Aishwarya; Thiruvenkatam, Vijay\u00a0and\u00a0Kirubakaran, Sivapriya, \u201cMutants of helicobacter pylori IMPDH: kinetics and in silico studies to determine the structural and functional role of key amino acids\u201d,\u00a0<em>Chemistry: An Asian Journal<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1002\/asia.202200125\" target=\"_blank\" rel=\"noopener\">10.1002\/asia.202200125<\/a>, Mar. 2022.<span><\/span><\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2021&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<ul>\n<li style=\"text-align: justify;\">Surendra, V. S.; Jayaram, V.; Muruganantham, M.;\u00a0Thiruvenkatam, Vijay; Vijayan, S.; Samarth, P.; Hill, H.; Bhardwaj, Anil; Mason, N. J.; Sivaraman, B., \u201cComplex structures synthesized in shock processing of nucleobases\u2013implications to the origins of life\u201d,\u00a0<em>International Journal of Astrobiology<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1017\/S1473550421000136\" target=\"_blank\" rel=\"noopener\">10.1017\/S1473550421000136<\/a>, vol. 20, no. 4, pp. 285-293, Aug. 2021.<\/li>\n<li style=\"text-align: justify;\">Ravi, Srimadhavi; Priya, Bhanu; Dubey, Pankaj; Thiruvenkatam, Vijay\u00a0and\u00a0Kirubakaran, Sivapriya, \u201cMolecular docking and molecular dynamics simulation studies of quinoline-3-carboxamide derivatives with DDR kinases\u2013selectivity studies towards ATM kinase\u201d,\u00a0<em>Chemistry,<\/em>\u00a0DOI:\u00a0<a href=\"https:\/\/doi.org\/10.3390\/chemistry3020036\" target=\"_blank\" rel=\"noopener\">10.3390\/chemistry3020036<\/a>, vol. 3, no. 2, pp. 511-524, Apr. 2021.<\/li>\n<li style=\"text-align: justify;\">Parwani, Kirti; Patel, Farhin;\u00a0Bhagwat, Pranav; Dilip, Haritha; Patel, Dhara;\u00a0Thiruvenkatam, Vijay\u00a0and Mandal, Palash, \u201cSwertiamarin mitigates nephropathy in high-fat diet\/streptozotocin-induced diabetic rats by inhibiting the formation of advanced glycation end products\u201d,\u00a0<em>Archives of Physiology and Biochemistry<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/\/10.1080\/13813455.2021.1987478\" target=\"_blank\" rel=\"noopener\">10.1080\/13813455.2021.1987478<\/a>, Oct. 2021.<\/li>\n<li style=\"text-align: justify;\">Nagarasu, Palaniyappan; Kundu, Anu;\u00a0Thiruvenkatam, Vijay; Raghavaiah, Pallepogu; Anthony, Savarimuthu Philip; Madhu, Vedichi, \u201cInvestigating the structure\u2013fluorescence properties of tetraphenylethylene fused imidazole AIEgens: reversible mechanofluorochromism and polymer matrix controlled fluorescence tuning\u201d,\u00a0<em>CrystEngComm,<\/em>\u00a0DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1039\/D1CE00561H\" target=\"_blank\" rel=\"noopener\">10.1039\/D1CE00561H<\/a>, vol. 23, no. 31, pp. 5403-5410, Jun. 2021.<\/li>\n<li style=\"text-align: justify;\">Mahapatra, Amarjyoti Das; Shaik, Althaf; Thiruvenkatam, Vijay\u00a0and\u00a0Datta, Bhaskar, \u201cSupramolecular architecture in sulfonylurea, sulfonyldiurea and sulfonyltriurea drugs: synthesis, X-ray structure and Hirshfeld surface analysis\u201d,\u00a0<em>Journal of Molecular Structure,<\/em>\u00a0DOI:\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.molstruc.2021.130158\" target=\"_blank\" rel=\"noopener\">10.1016\/j.molstruc.2021.130158<\/a>, vol. 1233, Feb. 2021.<\/li>\n<li style=\"text-align: justify;\">Al-Wahaibi, Lamya H.;\u00a0Shaik, Althaf; Elmorsy, Mohammed A.; Abdelbaky, Mohammed S. M.; Garcia-Granda, Santiago; Thamotharan, Subbiah;\u00a0Thiruvenkatam, Vijay\u00a0and El-Emam, Ali A., \u201cStructural insights of three 2,4-disubstituted dihydropyrimidine-5-carbonitriles as potential dihydrofolate reductase inhibitors\u201d,\u00a0<em>Molecules<\/em>, DOI:\u00a0<a href=\"https:\/\/doi.org\/10.3390\/molecules26113286\" target=\"_blank\" rel=\"noopener\">10.3390\/molecules26113286<\/a>, vol. 26, no. 11, May 2021.<\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2020&#8243; _builder_version=&#8221;4.21.0&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<ul>\n<li style=\"text-align: justify;\"><strong>Angira, Deekshi; Natarajan, Nalini<\/strong><span>; Dedania, Samir R.; Patel, Darshan H. and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cCharacterization of P. aeruginosa glucose 6- phosphate isomerase: a functional insight via in-vitro activity study\u201d,\u00a0<\/span><em>Current Topics in Medicinal Chemistry<\/em><span>, DOI:\u00a0<\/span><a href=\"https:\/\/doi.org\/10.2174\/1568026620666200820153751\" target=\"_blank\" rel=\"noopener\">10.2174\/1568026620666200820153751<\/a><span>, vol. 20, no. 29, pp. 2651-2661, Aug. 2020.<\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Angira, Deekshi; Shaik, Althaf<\/strong><span>\u00a0and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cStructural and strategic landscape of PIKK protein family and their inhibitors: an overview\u201d,\u00a0<\/span><em>Frontiers in Bioscience, Landmark Edition<\/em><span>, DOI:\u00a0<\/span><a href=\"https:\/\/doi.org\/10.2741\/4867\" target=\"_blank\" rel=\"noopener\">10.2741\/4867<\/a><span>, vol. 25, no. 8, pp. 1538-1567, Mar. 2020.<\/span><span><\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Hussain, Javeena; Angira, Deekshi; Hans, Tanya; Dubey, Pankaj; Kirubakaran, Sivapriya<\/strong><span>\u00a0and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cSynthesis and characterization of a new class of phenothiazine molecules with 10H-substituted morpholine &amp; piperidine derivatives: a structural insight\u201d,\u00a0<\/span><em>Journal of Molecular Structure,<\/em><span>\u00a0DOI:\u00a0<\/span><a href=\"http:\/\/dx.doi.org\/10.1016\/j.molstruc.2020.128546\" target=\"_blank\" rel=\"noopener\">10.1016\/j.molstruc.2020.128546<\/a><span>, vol. 1219, Jun. 2020.<\/span><span><\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Natarajan, Nalini; Shaik, Althaf<\/strong><span>\u00a0and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cRecombinant tumor suppressor TSC1 differentially interacts with\u00a0<\/span><i>Escherichia coli<\/i><span>\u00a0DnaK and human HSP70\u201d,\u00a0<\/span><em>ACS Omega,<\/em><span>\u00a0DOI:\u00a0<\/span><a href=\"https:\/\/doi.org\/10.1021\/acsomega.0c02480\" target=\"_blank\" rel=\"noopener\">10.1021\/acsomega.0c02480<\/a><span>, vol. 5, no. 30, pp. 19131-19139, Jul. 2020.<\/span><span><\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Natarajan, Nalini<\/strong><span>\u00a0and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cAn insight of scientific developments in TSC for better therapeutic strategy\u201d,\u00a0<\/span><em>Current Topics in Medicinal Chemistry<\/em><span>, DOI:\u00a0<\/span><a href=\"https:\/\/doi.org\/10.2174\/1568026620666200825170355\" target=\"_blank\" rel=\"noopener\">10.2174\/1568026620666200825170355<\/a><span>, vol. 20, no. 23, pp. 2080-2093, Aug. 2020.<\/span><span><\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Shaik, Althaf; Palaniswamy, Parimaladevi<\/strong><span>\u00a0and\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>, \u201cInvestigating structural aspects of pyridopyrimidinone derivatives, an important precursor in medicinal chemistry\u201d,\u00a0<\/span><em>Journal of Molecular Structure,<\/em><span>\u00a0DOI:\u00a0<\/span><a href=\"https:\/\/dx.doi.org\/10.1016\/j.molstruc.2020.129040\" target=\"_blank\" rel=\"noopener\">10.1016\/j.molstruc.2020.129040<\/a><span>, vol. 1224, Aug. 2020.<\/span><span><\/span><\/li>\n<li style=\"text-align: justify;\"><strong>Singh, Surendra V.<\/strong><span>; Vishakantaiah, Jayaram; Meka, Jaya K.; Sivaprahasam, Vijayan; Chandrasekaran, Vijayanand; Thombre, Rebecca;\u00a0<\/span><strong>Thiruvenkatam, Vijay<\/strong><span>; Mallya, Ambresh; Rajasekhar, Balabhadrapatruni N.; Muruganantham, Mariyappan; Datey, Akshay; Hill, Hugh; Bhardwaj, Anil; Jagadeesh, Gopalan; Reddy, Kalidevapura P. J.; Mason, Nigel J. and Sivaraman, Bhalamurugan, \u201cShock processing of amino acids leading to complex structures\u2014implications to the origin of life\u201d,\u00a0<\/span><em>Molecules,<\/em><span>\u00a0DOI:\u00a0<\/span><a href=\"https:\/\/doi.org\/10.3390\/molecules25235634\" target=\"_blank\" rel=\"noopener\">10.3390\/molecules25235634<\/a><span>, vol. 25, no. 23, Nov. 2020.<\/span><\/li>\n<\/ul>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2019&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<ul>\n<li><span style=\"font-size: 14px;\">Purushothaman, Gayathri, Deekshi Angira, and Vijay Thiruvenkatam. &#8220;Investigation of nicotinamide and isonicotinamide derivatives: A quantitative and qualitative structural analysis.&#8221; Journal of Molecular Structure 1197 (2019): 34-44.<\/span><\/li>\n<li><span style=\"font-size: 14px;\">Katla, Jagadish, Althaf Shaik, Rahul Dahiwadkar, Vijay Thiruvenkatam, and Sriram Kanvah. &#8220;One\u2010and Two\u2010Component Organogels Containing Cyanostilbene without any Auxiliary Substituents.&#8221; ChemPlusChem 84, no. 12 (2019): 1789-1795.<\/span><\/li>\n<li>Purushothaman, Gayathri, and Vijay Thiruvenkatam. &#8220;High yield expression of recombinant CD151 in E. coli and a structural insight into cholesterol binding domain.&#8221; Molecular Biotechnology 61 (2019): 905-915.<span style=\"font-size: 14px;\"><\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2018&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2017&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2016&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2015&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2014&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2013&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2012&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2011&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2010&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2009&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2008&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2007&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2006&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][et_pb_accordion_item title=&#8221;2005&#8243; _builder_version=&#8221;4.27.4&#8243; _module_preset=&#8221;default&#8221; global_colors_info=&#8221;{}&#8221; open=&#8221;off&#8221;]<\/p>\n<p>Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.<\/p>\n<p>[\/et_pb_accordion_item][\/et_pb_accordion][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.0.74&#8243; background_color=&#8221;#3c3d41&#8243; custom_padding=&#8221;0px||0px|&#8221; custom_padding_tablet=&#8221;0px||0px|&#8221; transparent_background=&#8221;off&#8221; padding_mobile=&#8221;on&#8221; global_module=&#8221;3921&#8243; saved_tabs=&#8221;all&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>MACROMOLECULAR AND CHEMICAL CRYSTALLOGRAPHY LAB (MCCL)Publications Chadha, Prashsti, Hiral Aghara, Harshrajsinh Solanki, Manali Patel, Dhrubjyoti Sharma, Vijay Thiruvenkatam, and PALASH MANDAL. &#8220;Modulation of TNF\u03b1-driven neuroinflammation by Gardenin A: Insights from In Vitro, In Vivo, and In Silico studies.&#8221;\u00a0Frontiers in Pharmacology 16: 1681403. DOI: https:\/\/doi.org\/10.3389\/fphar.2025.1681403\u00a0 Anandan A, Venkatesan P, Thiruvenkatam V, Percino MJ, Thamotharan S. Crystallographic [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"page-template-blank.php","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"class_list":["post-205467","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/pages\/205467","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/comments?post=205467"}],"version-history":[{"count":52,"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/pages\/205467\/revisions"}],"predecessor-version":[{"id":206504,"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/pages\/205467\/revisions\/206504"}],"wp:attachment":[{"href":"http:\/\/labs.iitgn.ac.in\/crystallab\/wp-json\/wp\/v2\/media?parent=205467"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}